DATE and PLACE of BIRTH: 29 August 1952, Ankara
RESEARCH INTEREST: Computer-Aided Drug Design, Artificial Intelligence, Machine Learning (Deep Learning), Synthesis, Aldose Reductase Enzyme Inhibition, Antioxidants, Anticancer, and Antiviral Compounds
EDUCATION and EXPERIENCE:
HIGH SCHOOL: Yenisehir College, 1969
UNIVERSITY: Gazi University, Faculty of Pharmacy, 1975
TUBITAK, Journal of Science and Technology, Editorial Assistant, 1975-1976
RESEARCH ASSISTANT, June 1978, Ankara Univ. Faculty of Pharmacy, Dept. Pharmaceutical Chemistry
GRADUATE STUDENT, January 1979, Ank. Univ. Dept. Pharmaceutical Chemistry
RESEARCH ASSOCIATE, University of Aberdeen, Department of Chemistry, 1982, British Council Grant, Supervisor: Dr. John R. Lewis Free-radical studies of ß-carboline compounds, synthesis and spectral studies of ß-carboline compounds Isolation of several alkaloids from Ruta plant., Nuclear Magnetic Resonance Training
Ph. D. (Thesis: Synthesis, Spectral Studies and Structure-Activity Relationships of Substituted Benzimidazoles: Application to Anticholinergic Activity), May 1983, Supervisor: Professor Ningur Noyanalpan
POSTDOCTORAL STUDY, Case Western Reserve University, Cleveland, OH, CWRU Grant, 1986 - 1988 Accomplishments: Computer-Automated Structure Evaluation (CASE), Applications of Artificial Intelligence and Expert Systems to Modeling of Drug Design, Design of Aldose Reductase Enzyme Inhibitors, Conformational Energy Calculations, Synthesis of Theoretically Designed Compounds, Biochemical Studies of Synthesized Compounds on Aldose Reductase Enzyme, Supervisor: Professor Gilles KLOPMAN
RESEARCH ASSOCIATE, Conformationally Modeling of Benzimidazole, Benzoxazole and Benzothiazole Compounds for Parasitic Toxicology Related Enzymes as a part of Antiparasitic and pressure-mediating drugs, NATO Grant, Collaboration with Professor Ningur Noyanalpan, Dr. John R. Lewis, 1989.
RESEARCH ASSOCIATE, Synthesis of Computer-Aided Drug Design Studies of Free Radical Scavenging Compounds as Immunomodulators and Anticarcinogens, The British Council Grant, 1991 - 1997 (Four times visit, every 3-4 months), Aberdeen, Scotland Collaboration with Dr. John R. Lewis.
VISITING PROFESSOR, Molecular Modeling Studies Regarding to Identification of Gly-Gln Receptor Sites in Brain, University of Missouri at Kansas City, School of Pharmacy, Kansas City MO, Collaboration with Professor Adeboye Adejare and Professor William Millington, 1998 -1999.
VISITING PROFESSOR, Artificial Intelligence Studies of NMDA Receptor Binding, Idaho State University, College of Pharmacy, 2003-2004, Pocatello, ID.
VISITING PROFESSOR, University of the Sciences, Philadelphia College of Pharmacy, Department of Pharmaceutical Sciences, 2006-2007, Philadelphia, PA.
VISITING PROFESSOR, University of the Sciences, Philadelphia College of Pharmacy, Department of Pharmaceutical Sciences, 2016, Philadelphia, PA.
VISITING PROFESSOR, University of the Sciences, Philadelphia College of Pharmacy, Department of Pharmaceutical Sciences, 2017, Philadelphia, PA.
VISITING PROFESSOR,
PROJECTS:
*) PROJECT COORDINATOR, The Synthesis and Evaluation of Novel Hydantoin Derivatives on Cataract Formation in Lens, Under Diabetic Condition: An Aldose Reductase Enzyme Inhibition Study, Ankara University R&D Grant, March 1989 - September 1990.
*) PROJECT COORDINATOR, Computer-Aided Drug Design in Terms of Molecular Orbital Energies and Conformational Analysis., Ankara University R&D Grant, 1993.
*) PROJECT COORDINATOR, Synthesis and Evaluation of Some Benzimidazoles as Immunomodulators and Antivirals, The British Council Grant, 1993.
*) PROJECT COORDINATOR, Synthesis and Biological Evaluation of Indole and Benzimidazole Compounds Bearing Retinodal Molecular Pathway, ECZACIBASI Drug Company Project, 1995.
*) PROJECT COORDINATOR, Chem-X, Molecular Modeling Studies on Drug Design, TUBITAK Project, 1996.
*) PROJECT RESEARCHER, Retinoidal-type of Benzimidazole Compounds And Their Effects on Free Radicals And Lipid Peroxidation, TUBITAK Project, 1996.
*) PROJECT COORDINATOR, Synthesis of Retinoidal Compounds And Their Effects on Free Radicals And Lipid Peroxidation, Ankara University R&D Grant, 1998.
*) PROJECT COORDINATOR, Retinodal Compounds And Their Effects on Cancer, DNA And Genotoxicity, TUBITAK Project, 1998.
*) PROJECT COORDINATOR, Synthesis and Radioprotective Effects of Novel Melatonin Derivatives, Ankara University, R&D Grant, 2003.
*) PROJECT COORDINATOR, Synthesis and Molecular Modeling Studies of Novel Heterocyclic Compounds as MDM2 Enzyme Inhibitors, Ankara University, R&D Grant, 2010-on progress.
*) PROJECT COORDINATOR, RAS Oncogene Protein Inhibitors as Anticancer Compounds, Ankara University, R&D Grant, 2011-on progress.
*) PROJECT RESEARCHER, Design and Synthesis of Novel PARP Inhibitors as Anticancer Compounds, Ankara University, R&D Grant, 2012-on progress.
ADMINISTRATIVE ASSIGNMENTS:
1. A.U., Faculty of Pharmacy, Symposium Organizing Committee, 1989 - 19922. Ankara University, The Commision of Computers, 1988 - 1992
3. Turkish Mountaineering Federation, President, 1989- 1991
4. Ankara University, Department of Physical Education and Sport, Vice President, 1988 - 1993
5. Ankara University Self-Evaluation Steering Committee, 2004 - date6. Ankara University Academic Assesment and Quality Management Committee, 2007 - date7. Ankara University Ethics Commission 2008-2012
MEMBERSHIPS:
1. American Chemical Society
2. Turkish Biochemistry Society
3. The Society of Pharmaceutical Sciences
4. Nature Sports Society (Founder member)
HOBBIES: Playing piano and guitar, nature sports, swimming, sub aqua, tennis, chess and bridge